This course will be streamed only for the registered participants. Applications close on 27 April, and registered participants have until 30 April to pay their registration fee and thus confirm their participation. Plese visit the SIB web page for more information.

Confirmed speaker: Frédérique Lisacek, Sylvie Ricard-Blum, Kiyoko Aoki-Kinoshita, Serge Perez, Julien Mariethoz et François Bonnardel

Overview:
Often enough the word glycoprotein is used yet the “glyco” part is hardly ever detailed. This is for instance the case with viruses in which surface spiking proteins are abbreviated GP and numbered like HIV GP120, but remain depicted as a smooth fist-like structure. In reality, glycan molecules decorate a broad variety of surface or secreted proteins and the literature is filled with unnoticed references focusing on the “glyco” part. This course is an opportunity to update and extend your knowledge of glycoproteins through the use of bioinformatics resources collectively called “glycoinformatics”. We will provide an overview of the challenging questions raised by the study of glycans as non-template driven molecules and the solutions that are currently proposed to store, search, analyse and visualise the effect(s) of protein glycosylation on protein structure, function(s) and interactions.