The Department of Biomedicine at the Faculty of Health at Aarhus University invites applications for a position as postdoctoral fellow within the research area as of Organelle Quality Control by Autophagy per 1st August 2024 or as soon as possible thereafter. The position is a fixed-term, full-time position for 4 years.

The Department of Biomedicine prioritizes diversity and a good work environment, as this is a prerequisite for groundbreaking research. In a dynamic and international research environment, dedicated employees are looking to generate new knowledge within biomedical research areas such as infection and inflammation, membranes, neuroscience and personalized medicine. The Department of Biomedicine provides research-based teaching of the highest quality and is responsible for a large part of the medical degree programme. Academic staff contribute to the teaching. English is the preferred language in the laboratory, at meetings and at seminars. The department employs approx. 500 people from all over the world, and they make use of the department's modern laboratory-, core- and animal facilities. The Department of Biomedicine focuses on innovation, entrepreneurship and collaboration with business and industry, and numerous researchers from the department have established companies to develop new medicinal treatments founded in strong scientific basic research. You can read more about the department here and about the faculty here.

About the research project
Autophagy is a catabolic process highly conserved among eukaryotes, which is involved in the degradation of long-lived proteins, aberrant complexes and aggregates, dysfunctional and superfluous organelles, and intracellular pathogens. Structures targeted to destruction, including intracellular organelles, are sequestered by double-membrane vesicles called autophagosomes and delivered to lysosomes for turnover. The central players of autophagy are the autophagy-related (ATG) proteins. Autophagy can be highly selective and target specific unwanted structures using the so-called selective autophagy receptors (SARs) and various adaptor proteins.

The overall aim of the project is to understand the relevance of autophagy, ATG proteins and SARs in the quality control of intracellular organelles such as the endoplasmic reticulum, mitochondria and peroxisomes. The overall idea is to identify how these players sense and then mediate the turnover of local dysfunctions in these organelles.Your job responsibilities
As Postdoc in cell biology/biochemistry, your position is primarily research-based but may also involve teaching assignments. You will contribute to the development of the department through research of high international quality. In your daily work, you will work closely with colleagues on related projects, but not only.

More information HERE.

Der Lehrstuhl für Physiologie & Pathophysiologie sucht eine/n

Senior Lecturer (m/w/d)

Kennzahl: LS-PHYSIO-2024-002733

Bewerbungsfrist: 09.05.2024

Ihre Aufgaben in dieser Position beinhalten:

Selbstständige Durchführung von Lehrveranstaltungen und Abhaltung von Prüfungen im Ausmaß der kollektivvertraglichen Bestimmungen (Regelausmaß 16 Semesterstunden)
Betreuung von Studierenden
Mitarbeit im Forschungsbetrieb und an Forschungsprojekten auf dem Gebiet der Physiologie und Pathophysiologie
Übernahme von Organisations- und Verwaltungsaufgaben
 

Für diese Position bringen Sie folgende Qualifikationen und Kenntnisse mit:

Abgeschlossenes medizinisches oder naturwissenschaftliches Doktorats-/PhD-Studium mit ausgezeichneten Kenntnissen im Bereich Physiologie und Pathophysiologie
Hochschuldidaktische Aus- und Weiterbildung
Erfahrung im universitären Lehr- und Prüfungsbetrieb
Sehr gute Deutsch- und Englischkenntnisse (Sprachniveau C1)
 

Idealerweise zählen zu Ihrem Profil:

Interesse an der eigenen wissenschaftlichen Weiterqualifikation (z.B. Habilitation)
Lehr- und Prüfungserfahrung im Bereich Physiologie und Pathophysiologie
Fähigkeit zur selbstständigen Arbeit wie auch zur Arbeit im Team
 

Eintrittsdatum: 03.06.2024

befristet auf 2 Jahre

mit der Option auf Verlängerung

Beschäftigungsausmaß: 100%

Einstufung in die Verwendungsgruppe B1 nach Kollektivvertrag für ArbeitnehmerInnen der Universitäten.

Webseite

The Dengjel and De Virgilio Labs at the Dept. of Biology, University of Fribourg are interested in cellular
signal transduction and protein homeostasis. We characterize molecular pathways critical for cell
homeostasis, autophagy regulation and autophagosome biogenesis and employ mammalian and/or yeast
cell culture models, protein biochemistry, and mass spectrometry-based proteomics (1-4). Current projects
are supported by third-party grants from the Swiss National Science Foundation and private foundations.
We look for highly motivated PhD students with interests in the areas outlined above. Excellent
communication skills in English are of benefit.

We offer:
• a stimulating, interdisciplinary scientific environment
• state-of-the-art central facilities for proteomic, imaging and bioinformatic analyses
• a coordinated graduate program (https://www.unifr.ch/bio/en/studies/graduate-school-fglm/)
• a competitive Swiss salary

Fribourg and its University are located in the heart of Switzerland, 30 min from Bern and 50 min from
Lausanne. Research and life conditions are excellent. Major facilities are either on campus or available
through national networks. The Dengjel Lab is actively engaged in SKINTEGRITY.CH and Life Science
Switzerland (LS²).

The starting date for this position is July 1st, 2024 (or later). Interested candidates should send a SINGLE
PDF application including a CV, a brief statement of their research interests, a copy of their MSc diploma,
and names of three referees by email to: stephanie.kaeser-pebernard@unifr.ch

Der Rektor verantwortet die Lehre an der ETH Zürich. Er legt seine Abteilung «Lehrtechnologie- und -entwicklung» mit seinem Stabsbereich «Strategische Initiativen» zu einer neuen Abteilung zusammen, die ihm direkt unterstellt ist. Ihre Bezeichnung steht noch nicht fest. Sie ist die zentrale Einheit zur Unterstützung aller an der Lehre beteiligter Personen in Fragen rund um die Entwicklung ihrer Lehr- und Lernformen, der Curricula und der in der Lehre verwendeten Technologien. Zudem setzt die Abteilung grosse, ETH-weite Projekte um. Diese dienen der Weiterentwicklung der Lehre, der Komplettierung der Lernerfahrung der Studierenden und der Unterstützung der langfristigen strategischen Ausrichtung der Lehre.

Stellenbeschreibung
In dieser Funktion führen Sie die beiden bisher getrennten Einheiten zusammen. Sie sind für die fachliche, personelle und organisatorische Führung und Ausrichtung der Abteilung verantwortlich. Zu Ihren Geschäften gehören die Umsetzung von Lehrprojekten, wie z.B. die Förderung projektbasierter Lehre oder die Begleitung der Curriculumsentwicklungen der Departemente der ETH. Sie pflegen die Zusammenarbeit mit dem Netzwerk der Lehrspezialistinnen und Lehrspezialisten an den Departementen. Sie arbeiten eng mit dem Rektor und dem Prorektor Curriculumsentwicklung zusammen und setzen mit ihnen eine gemeinsame Strategie für den Lehrbereich um. 

https://jobs.ethz.ch/job/view/JOPG_ethz_m6Zh62nPnB15CQECbN

WHO WE ARE

Disco Pharmaceuticals is a young ETH spin-off company based in Zurich/Switzerland and Cologne/Germany.
We leverage a novel mass spectrometric technology to investigate processes that are fundamental to
cancer biology. We combine methodologies in cell biology, biochemistry, mass spectrometry with
computational tools to identify proteins selectively expressed on cancer cells. Our ultimate goal is to
develop innovative therapies for cancers with high unmet clinical need.

POSITION

To strengthen our activities, DISCO Pharmaceuticals is looking for a talented full-time research associate to
join our international team. The successful candidate will be based in Zurich and work with a dynamic and
highly motivated team to drive the development of novel antibody therapeutics for indications with high
unmet medical needs. Given the nature of the duties and responsibilities, this in a mostly on-site role.

CONTACT

For further information and to apply, please contact Emanuela Milani, emanuela@discopharma.de

More information in pdf.

WHO WE ARE

Disco Pharmaceuticals is a young ETH spin-off company based in Zurich/Switzerland and Cologne/Germany. We leverage a novel mass spectrometric technology to investigate processes that are fundamental to cancer biology. We combine methodologies in cell biology, biochemistry, mass spectrometry with computational tools to identify proteins selectively expressed on cancer cells. Our ultimate goal is to develop innovative therapies for cancers with high unmet clinical need.

POSITION

To strengthen our activities, DISCO Pharmaceuticals is looking for an enthusiastic scientist to join our international team. Candidates should have a solid background in protein chemistry and molecular biology, with an interest to apply their skills for development of novel cancer therapies. The successful candidate will be based in Zurich and work with a dynamic and highly motivated team to drive the development of novel antibody therapeutics for indications with high unmet medical need. The candidate will collaborate with colleagues in computational biology, biology and antibody discovery.

CONTACT

For further information and to apply, please contact Emanuela Milani, emanuela@discopharma.de

More information in pdf.